Major writers/series I'm into:
H.P. Lovecraft (no other horror writer comes close to his style)
Warhammer 40,000 (tie-in fiction but in recent years has stood on its own in the New York Times Bestsellers list)
Legend of Drizzt (R.A. Salvatore)
and whatever else that catches my eye if I'm wandering a bookstore.
Huge comic fan as well, DC/Marvel/Image etc.